Star Trek: Infinite Space will be the first ST game in a while (since Online I think). Taking place in the main Star Trek Universe (not in the Abrams-verse), Infinite Space is set in the time of the Next Generation/Deep Space Nine and looks like a Dominion War kind of thing-
Star Trek® - Infinite Space from Gameforge on Vimeo.
I don't remember the Klingons being in open war with the Federation and I was a huge Trek fan, but hey who knows... the trailer looks nice.
The game will also be free to play and based entirely in browser- we'll see I guess. I'm still waiting for some new graphic adventures. Hell, even the action/RPG/RTS stuff would be fine. This license all but disappeared over the last few years.
Official Site
